Biogenesis of Circular RNAs

Vicens, Quentin; Westhof, Eric

Biogenesis of Circular RNAs

2014

Vicens, Quentin | Westhof, Eric

Circular RNAs are generated during splicing through various mechanisms. Ashwal-Fluss et al. demonstrate that exon circularization and linear splicing compete with each other in a tissue-specific fashion, and Zhang et al. show that exon circularization depends on flanking intronic complementary sequences. Both papers show that several types of circular RNA transcripts can be produced from a single gene.

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