Plants and animals share functionally common bacterial virulence factors
2000
Rahme, L.G. | Ausubel, F.M. | Cao, H. | Drenkard, E. | Goumnerov, B.C. | Lau, G.W. | Mahajan-Miklos, S. | Plotnikova, J. | Tan, M.W. | Tsongalis, J.
By exploiting the ability of Pseudomonas aeruginosa to infect a variety of vertebrate and nonvertebrate hosts, we have developed model systems that use plants and nematodes as adjuncts to mammalian models to help elucidate the molecular basis of P. aeruginosa pathogenesis. Our studies reveal a remarkable degree of conservation in the virulence mechanisms used by P. aeruginosa to infect hosts of divergent evolutionary origins.
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书目信息
Proceedings of the National Academy of Sciences of the United States of America
卷
97
期
16
页码
8815
- 8821
ISSN
0027-8424
其它主题
Experimental infections; Plant models for human diseases; Biological evolution
语言
英语
注释
Paper presented at the colloquium "virulence and defense in host-pathogen interactions: common features between plants and animals" held december 9-11, 1999, irvine, california.
2019-12-04
许可
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类型
Journal Article; Text
2024-02-28
MODS