Antimicrobially active terpenes cause K⁺ leakage in E. coli cells
2005
Griffin, S.G. | Wyllie, S.G. | Markham, J.L.
The known antimicrobially active oxygenated terpenes, carvone, terpinen-4-ol, alpha-terpineol, carveol and myrtenol were found to cause significant K(+) leakage from E. coli cells. In contrast, the relatively inactive oxygenated terpenes, 1,8-cineole and p-menth-6-ene-2,8-diol, did not cause significant K(+) leakage. Slight structural differences between active terpenes were found to affect the rate of K(+) leakage from E. coli cells. The membrane permeabilizing effect of the active terpenes is considered a significant factor in their antimicrobial activity.
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