Alkaloids of Galanthus elwesii
1995
Latvala, A. | Onur, M.A. | Gozler, T. | Linden, A. | Kivcak, B. | Hesse, M.
Six new lycorenine-type alkaloids, (+)-5-methyoxy-9-O demethylhomolycorine, (+)-galwesine,(+)-9 O-demethylgalwesine, (+)-16-hydroxygalwesine, (+) 16-hydroxy-9-O-demethylgalwesine and galasine, were isolated from whole plants of Galanthus elwesii. Additionally, 12 known alkaloids, (-)-galanthamine, (-)-sanguinine, (-)-leucotamine, (-)-O-methylleucotamine, (+/-)-narwedine, (-)-N-demethylgalanthamine, (+) 11-hydroxyvittatine, (+)-9-O-demethylhomolycorine, (-)-lycorine, (-)-galanthine, hordenine, and (E)-N-feruloyltyramine were also obtained. Of these alkaloids, only galanthamine and lycorine have been isolated previously from G. elwesii. Identification and structural elucidation were achieved using spectrometric techniques.
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