Malignant peripheral nerve sheath tumour of the urinary bladder in a cat
2012
Pavia, P. R. | Havig, M. E. | Donovan, T. A. | Craft, D.
A 14‐year‐old domestic shorthair cat presented with a 5‐month history of urinary incontinence and inappro‐priate elimination. Ultrasonography revealed a well‐marginated, vascular mass of mixed echogenicity ex‐tending from the dorsal wall of the urinary bladder into the lumen. Partial cystectomy was performed for re‐moval of the urinary bladder mass; histopathological evaluation revealed a spindle cell neoplasm with a prominent palisading pattern. Histomorphologic features and immunohistochemical demonstration of vimentin, glial fibrillary acidic protein and S‐100 protein, combined with negativity for smooth muscle actin and desmin were consistent with malignant peripheral nerve sheath tumour. This case report describes a novel location of malignant peripheral nerve sheath tumour; to the authors' knowledge, the bladder has not been described as a site of origin in the cat or any other domestic species.
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