Total body content of copper and other essential metals in rats fed fructose or starch
1988
Failla, M.L. | Seidel, K.E.
The effects of dietary carbohydrate and copper on whole body levels of copper and other essential minerals were investigated. Weaned male rats were pair-fed diets containing 62% fructose or cornstarch with either adequate (6-7 mg/kg) or deficient (0.5-0.7 mg/kg) copper (Cu) for 32-33 days. Recommended levels of other minerals were present in all diets. Total copper in whole body was approximately 2-fold higher in rats fed copper-supplemented diets than copper-deficient diets and was independent of the type of dietary carbohydrate. Whole body levels of zinc, iron, manganese and magnesium were independent of dietary copper and carbohydrate. Selenium content of rats fed copper-deficient diet with fructose was 35% higher than in those fed copper-adequate diet with fructose. Rats fed the copper-deficient diet containing starch had a whole body calcium level 17-23% lower than that of the other dietary groups. These results demonstrate that the copper-carbohydrate interaction is not a result of carbohydrate-dependent effects on the retention of dietary copper and other essential minerals.
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