Ergosterol Peroxide, an Apoptosis-Inducing Component Isolated from Sarcodon aspratus (Berk.) S. Ito
2005
TAKEI, Toshiyuki | Yoshida, Mitsuru | OHNISHI-KAMEYAMA, Mayumi | Kobori, Masuko
Among the lipophilic extracts of seven traditional edible mushrooms, the acetone extract of Sarcodon aspratus markedly inhibited the growth of HL60 human leukemia cells and induced apoptosis after 24 h incubation. The major active component was identified as ergosterol peroxide by NMR and ESI-MS analysis. Ergosterol peroxide completely inhibited growth and induced apoptosis of HL60 cells at a concentration of 25 μM.
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书目信息
Bioscience, biotechnology, and biochemistry
卷
69
期
1
页码
212
- 215
ISSN
1347-6947
出版者
Japan Society for Bioscience, Biotechnology, and Agrochemistry
其它主题
Sarcodon aspratus (berk.) s. ito; Growth retardation; Lipophilicity; Ergosterol peroxide; Sarcodon; Hl60 human leukemia cells
语言
英语
注释
Nal-ap-2-clean
类型
Journal Article; Text
2024-02-28
MODS