Cascade Multiple Diels–Alder Reactions of Styrene Derivatives with Maleimide or Maleic Anhydride

Yoshioka, Shohei; Aoyama, Hiroshi; Fujioka, Hiromichi; Arisawa, Mitsuhiro

Cascade Multiple Diels–Alder Reactions of Styrene Derivatives with Maleimide or Maleic Anhydride

2018

Yoshioka, Shohei | Aoyama, Hiroshi | Fujioka, Hiromichi | Arisawa, Mitsuhiro

We developed novel one-pot multiple Diels–Alder reactions, which are frequently used in the construction of six-membered rings in functional molecular synthesis. We report triple and double Diels–Alder reactions with styrene derivatives, where the secondary Diels–Alder reaction takes place at a different position from that of the conventional Wagner-Jauregg reaction.

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