Mn(III)-promoted synthesis of spiroannular tricyclic scaffolds via sulfonylation/dearomatization of biaryl ynones

Zhou, Li; Xia, Yu; Wang, Yu-Zhao; Fang, Jun-Dan; Liu, Xue-Yuan

Mn(III)-promoted synthesis of spiroannular tricyclic scaffolds via sulfonylation/dearomatization of biaryl ynones

2019

Zhou, Li | Xia, Yu | Wang, Yu-Zhao | Fang, Jun-Dan | Liu, Xue-Yuan

A Mn(III)-promoted radical oxidative ipso-annulation reaction of biaryl ynones with sodium sulfinates to construct various substituted spiro[5.5]trienones has been explored in this study. This protocol is characterized by mild reaction conditions, good substrates functional group compatibility, cheap and easily prepared Mn(OAc)3·2H2O, and it demonstrates a simple operation.

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