Neuronal and Generalized Ceroid-Lipofuscinosis in a Cocker Spaniel

Wilkie, J. S Nimmo; Hudson, E. B.

Neuronal and Generalized Ceroid-Lipofuscinosis in a Cocker Spaniel

1982

Wilkie, J. S Nimmo | Hudson, E. B.

An 18-month-old cocker spaniel with a progressive central nervous system disorder had neuronal ceroid-lipofuscinosis and storage of these pigments in intestinal, blood vessel, and splenic smooth muscle and in pancreatic, hepatic, and renal parenchymal cells. The disease resembles that documented in four other dogs of this breed. No cause was identified in our dog, but possible pathogenetic mechanisms are discussed.

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