Tumor cell toxicity of hypericin and related analogs
2001
Wills, N.J. | Park, J (James) | Wen, J. | Kesavan, S. | Kraus, G.A. | Petrich, J.W. | Carpenter, S.
A series of hypericin analogs were found to differ in their cytotoxic activity induced by ambient light levels. These analogs vary in their ability to partition into cells, to generate singlet oxygen as well as in other photophysical properties. The data suggest that the biological activity of hypericin is due to a combination of factors whose roles may vary under different circumstances.
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书目信息
其它主题
Perylene; Analogs & derivatives; Singlet oxygen; Tumor cells; Cultured; Photosensitizing agents; Photochemotherapy
语言
英语
类型
Journal Article; Text
2024-02-28
MODS