Towards accurate imputation of quantitative genetic interactions
2009
Ulitsky, Igor | Krogan, Nevan J. | Shamir, Ron
Recent technological breakthroughs have enabled high-throughput quantitative measurements of hundreds of thousands of genetic interactions among hundreds of genes in Saccharomyces cerevisiae. However, these assays often fail to measure the genetic interactions among up to 40% of the studied gene pairs. Here we present a novel method, which combines genetic interaction data together with diverse genomic data, to quantitatively impute these missing interactions. We also present data on almost 190,000 novel interactions.
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书目信息
Genome biology
卷
10
期
12
页码
2290
- 2290
ISSN
1474-760X
出版者
Springer-Verlag
语言
英语
许可
//data.crossref.org/schemas/AccessIndicators.xsd:license_ref>http://purl.org/eprint/accessRights/OpenAccess | //data.crossref.org/schemas/AccessIndicators.xsd:program>//data.crossref.org/schemas/AccessIndicators.xsd:license_ref> | //data.crossref.org/schemas/AccessIndicators.xsd:program>
类型
Journal Article; Text
2024-02-28
MODS