Tandem Reaction of Tertiary Enamides as a Synthetic Strategy to Construct the Fused N-Pentacyclic Skeleton of Erythrina Alkaloid Derivatives
2020
Yang, Hanlin | Li, Wenzhong | Xu, Xin-Ming | Wang, Zu-Li
An exquisite protocol to the synthesis of erythrina-related structural derivatives was developed, which is composed of a nucleophilic addition of tertiary enamides to ketonic carbonyls and the trapping of acyliminium by an aromatic unit. This protocol afforded a powerful method for the construction of diverse fused N-pentacyclic skeletons in high efficiency and excellent diastereoselectivity by just using different acid catalysts.
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书目信息
Organic letters
卷
22
期
22
页码
8814
- 8818
ISSN
1523-7052
出版者
American Chemical Society
其它主题
Lewis bases; Diastereoselectivity
语言
英语
注释
Nal-ap-2-clean
类型
Journal Article; Text
2024-02-28
MODS