Synthesis of 1-aryl indoles via coupling reaction of indoles and aryl halides catalyzed by CuI/metformin
2014
Chen, Hu | Lei, Min | Hu, Lihong
Ullmann-type C–N coupling reaction has been developed for the synthesis of 1-aryl indole derivatives by indoles and aryl halides in the presence of CuI/metformin (CuI/Met) in DMF. This method is very easy, rapid, and high yielding reaction for the synthesis of 1-aryl indoles. In particular, the metformin, which is used as ligand, is inexpensive and nontoxic that is considered to be relatively environmentally benign.
显示更多 [+] 显示较少 [-]AGROVOC关键词
书目信息
Tetrahedron
卷
70
页码
5626
- 5631
ISSN
0040-4020
出版者
Elsevier Ltd
其它主题
Aryl halide; C–n coupling reaction; Metformin; Metformin; Ullmann-type reaction
语言
英语
类型
Journal Article; Text
2024-02-28
MODS