Batch Fermentation Model of Propionic Acid Production by Propionibacterium acidipropionici in Different Carbon Sources
2008
Coral, Jefferson | Porto de Souza Vandenberghe, Luciana | Parada, José Luis | Pandey, Ashok | Soccol, Carlos Ricardo
Propionic acid (PA) is widely used as additive in animal feed and also in the manufacturing of cellulose-based plastics, herbicides, and perfumes. Salts of propionic acid are used as preservative in food. PA is mainly produced by chemical synthesis. Nowadays, PA production by fermentation of low-cost industrial wastes or renewable sources has been an interesting alternative. In the present investigation, PA production by Propionibacterium acidipropionici ATCC 4965 was studied using a basal medium with sugarcane molasses (BMSM), glycerol or lactate (BML) in small batch fermentation at 30 and 36 °C. Bacterial growth was carried out under low dissolved oxygen concentration and without pH control. Results indicated that P. acidipropionici produced more biomass in BMSM than in other media at 30 °C (7.55 g l⁻¹) as well as at 36 °C (3.71 g l⁻¹). PA and biomass production were higher at 30 °C than at 36 °C in all cases studied. The best productivity was obtained by using BML (0.113 g l⁻¹ h⁻¹), although the yielding of this metabolite was higher when using glycerol as carbon source (0.724 g g⁻¹) because there was no detection of acetic acid. By the way, when using the other two carbon sources, acetic acid emerged as an undesirable by-product for further PA purification.
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