A new flavonol glycoside from the medicinal halophyte Suaeda fruticosa
2014
Oueslati, Samia | Ksouri, Riadh | Pichette, André | Lavoie, Serge | Girard-Lalancette, Karl | Mshvildadze, Vakhtang | Abdelly, Chedly | Legault, Jean
A new flavonol glycoside, namely 3-(α-rhamnopyranosyl-(1 → 2)-[β-xylopyranosyl-(1 → 6)]-β-glucopyranosyloxy) isorhamnetin was reported from methanol extracts of aerial parts of Suaeda fruticosa for the first time. In this work, liquid chromatography coupled to atmospheric pressure chemical ionisation mass spectrometry, high-resolution mass spectrometry and nuclear magnetic resonance spectroscopy were used to identify this new compound. Structure was elucidated on the basis of extensive spectroscopic analysis, including HSQC, HMBC and ¹H– ¹H COSY. Antioxidant potentialities of a pure compound were evaluated. The estimation of antioxidant capacities using oxygen radical absorbance capacity (ORAC method) and a cell based-assay (WS1) indicated that this new flavonol exhibited the highest antioxidant activities with an ORAC value of 5.0 ± 0.3 μmol Trolox/μmol and inhibited the t BH-induced oxidation of 2′,7′-dichlorofluorescin with an IC ₅₀ value of 4.9 ± 0.6 μM.
显示更多 [+] 显示较少 [-]