Fast computer search for similar DNA sequences
1984
Bishop, M. J. (Martin J) | Thompson, E.
An extremely fast method of searching a nucleic acid sequence database against a probe sequence is described. The method is based on the detection of deviation from expected number and deviation from random spatial distribution of sub-sequences which are unique within a sequence, and shared between that sequence and the probe. On an IBM 3081 computer, total search of an encoded form of the EMBL nucleic acid sequence database with a 1 kbase probe sequence is completed in a few seconds. Previous best methods for a similar task required a few minutes.
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书目信息
Nucleic acids research
卷
12
期
13
页码
5471
- 5474
ISSN
0305-1048
其它主题
Emblscan; Base sequence; Sequence homology; Nucleotide sequences; Computer analysis; Species specificity; Probability
语言
英语
类型
Journal Article; Text
2024-02-28
MODS