Retinol binding protein in serum of xerophthalmic malnourished children before and after treatment at a nutrition center
1977
Venkataswamy, G. | Glover, John | Cobby, Mark | Pirie, Antoinette
Extract: Retinol binding protein and prealbumin levels were measured in the serum of children who were both malnourished and showed clinical signs of xerophthalmia. The more severe the xerophthalmia the lower the concentration of retinol binding protein and prealbumin in serum. Thirty four children were admitted to the Nutrition Rehabilitation Center and were observed for a sufficient length of time for an assessment to be made of the effect of treatment on vision. None became blind but one had seriously impaired vision and one other lost one eye. The remaining children had normal vision or vision that although impaired would still enable them to lead an active life. It is suggested that the children needed protein from which to synthesize retinol binding protein before normal retinol transport could be re established.
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