Catalyst-free, efficient and one pot protocol for synthesis of nitriles from aldehydes using glycerol as green solvent
2017
Ingale, Ajit P. | Patil, Shripad M. | Shinde, Sandeep V.
We described herein the novel, efficient and one-pot catalyst free protocol for the synthesis of nitriles from aldehydes by using hydroxyl amine hydrochlorides in glycerol as a green solvent. This protocol was efficiently used for transformation of aromatic aldehydes bearing electron-withdrawing and electron-donating groups into a aryl nitriles in good to excellent yields. The methodology offers a very simple, efficient and environmentally benign procedure.
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书目信息
出版者
Elsevier Ltd
其它主题
Nitriles; Nitriles
语言
英语
类型
Journal Article; Text
2024-02-28
MODS