Effects of maternal methyl-supplement diet on hippocampal glucocorticoid receptor mRNA expression in rats selected for behavior
2010
Herbeck, Yu. E. | Os'kina, I. N. | Gulevich, R. G. | Plyusnina, I. Z.
In the present work, we study glucocorticoid receptor (GR) gene expression in gray rats selected for aggressive and domestic behavior, as well as in offspring of mothers with methyl-supplemented diet during pregnancy. Tame selection is associated with increased GR mRNA expression as compared with aggressive rats, whereas maternal methyl-supplemented diet inhibits GR activity in tame rats. GR gene promoter methylation is an important way of altering GR expression.
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书目信息
Cytology and genetics
卷
44
期
2
页码
108
- 113
ISSN
0095-4527
出版者
Allerton Press, Inc.
其它主题
Maternal effect
语言
英语
注释
Includes references
类型
Journal Article; Text
2024-02-28
MODS