Effects of NO-modulating agents on the development of acute painful reaction in rats
2008
Dyuizen, I. V | Lamash, N. E
Painful reaction of rats to intraperitoneal injections of L-arginine, Nω-nitro-L-arginine, and agmatine was studied on the model of formalin-induced inflammation. All drugs exhibited a dubious effect on the patterns of nociceptive behavior depending on the phase of painful reaction. The dynamics of nitrate/nitrite content in animal blood and serum indicated the presence of NO-dependent and NO-independent components in the mechanisms of pharmacological effects of these drugs.
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书目信息
Bulletin of experimental biology and medicine. Bi︠︡ulletenʹ ėksperimentalʹnoĭ biologii i medit︠︡siny
卷
146
期
2
页码
214
- 217
ISSN
0007-4888
出版者
Boston : Springer US
其它主题
Analgesia; Intraperitoneal; Injections; Wistar; Pain measurement; Male; Antagonists & inhibitors; Agmatine; Drug effects; Chemically induced; Nitroarginine
语言
英语
类型
Journal Article; Text
2024-02-28
MODS