Distinct Kinetics of Effector CD8⁺ Cytotoxic T Cells after Infection with Trypanosoma cruzi in Naïve or Vaccinated Mice
2006
Tzelepis, Fanny | Alencar, Bruna C. G de | Penido, Marcus L. O. | Gazzinelli, Ricardo T. | Persechini, Pedro M. | Rodrigues, Mauricio M.
The kinetics of effector CD8⁺-T-cell responses to specific Trypanosoma cruzi epitopes was investigated after challenge. Our results suggest that the delayed kinetics differs from that observed in other microbial infections and facilitates the establishment of the disease in naïve mice. In contrast, in vaccinated mice, the swift CD8⁺-T-cell response helps host survival after challenge.
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书目信息
Infection and immunity
卷
74
期
4
页码
2477
- 2481
ISSN
0019-9567
出版者
American Society for Microbiology
其它主题
Epitopes
语言
英语
注释
Includes references
许可
//data.crossref.org/schemas/AccessIndicators.xsd:license_ref>http://purl.org/eprint/accessRights/OpenAccess | //data.crossref.org/schemas/AccessIndicators.xsd:program>//data.crossref.org/schemas/AccessIndicators.xsd:license_ref> | //data.crossref.org/schemas/AccessIndicators.xsd:program>
类型
Journal Article; Text
2024-02-28
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