Chemical profiling and total thickness-excised wound-healing activity of Pistacia lentiscus L. fruits growing in Algeria
2016
Boukeloua, Ahmed | Belkhiri, Abdelmalik | Yilmaz, Mustafa Abdullah | Temel, Hamdi | Sabatini, Sabrina
The aim of this study was to determine the chemical characterization and to assess full-thickness-excised wound-healing activity of the oil of Pistacia lentiscus L. fruits grown in Algeria. The fatty acid composition of P. lentiscus L. extracts were analyzed by GC–MS and their total protein amounts were determined by elemental analysis. Total thickness-excised wound-healing activity of hexane extract was carried out on rabbits; comparing oil and wax effects. The results showed that P. lentiscus L. fruits contain considerable levels of oil and protein. Additionally, oleic (46.91 ± 1.03, 48.34 ± 0.07) in hexane and cold pressure extracts, respectively, palmitic (25.75 ± 0.82, 25.44 ± 0.65) and linoleic (20.59 ± 0.03, 20.27 ± 0.81) acids were the major fatty acids. Wound-healing activity was significantly higher in P. lentiscus L. fatty oil compared to the wax, therefore, fats refining is wildly recommended.
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