DNA logic assembly powered by a triplex-helix molecular switch for extracellular pH imaging

Qi, Hongjie; Yue, Shuzhen; Bi, Sai; Ding, Caifeng; Song, Weiling

DNA logic assembly powered by a triplex-helix molecular switch for extracellular pH imaging

2018

Qi, Hongjie | Yue, Shuzhen | Bi, Sai | Ding, Caifeng | Song, Weiling

We demonstrate a strategy for pH-programmable self-assembly of DNA nanostructures by taking advantage of the pH dependence of reverse Hoogsteen interactions for a triplex-helix molecular switch. This strategy is successfully applied to the construction of molecular logic gates and imaging of extracellular pH.

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