Methods to improve the solubility of therapeutical natural products: a review
2021
Jain, Harsha | Chella, Naveen
Many natural substances are efficient in vitro and in vivo for the treatment of various disorders. However, treatment is often limited by their low bioavailability, water solubility and permeation. As a consequence, drugs are administered frequently and in large doses. There is therefore a need for techniques to enhance the solubility, permeability and the stability. Here, we review methods to improve solubility using particle engineering, complexation, solid dispersion, solubilization, chemical modifications and use of nanocarriers.
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书目信息
出版者
John Wiley & Sons, Ltd
其它主题
Environmental science; Water solubility; Nanocarriers
语言
英语
注释
Nal-ap-2-clean
Review
类型
Journal Article; Text
2024-02-28
MODS