A new myrsinol-type diterpene polyester from Euphorbia dracunculoides Lam
2015
Wang, Li | Yang, Jing | Chi, Yu-Qian | Ouyang, Wen-Bin | Zang, Zhen | Huang, Sheng-Xiong | Cao, Pei | Zhao, Yong
A new myrsinol-type diterpene polyester, 14-deoxo-3β- O -propinoyl-2α,5α,7β,15β-tetra- O -acetyl-14α- O -benzoyl-myrsinol (1), and its known analogue, 14-deoxo-3β- O -prorionyl-5α,15β-di- O -acetyl-7β- O -nicotinoyl-myrsinol-14β-acetate (2), together with a monoterpenoid, pubinernoid A (3), two indole alkaloids, neoechinulin A (4) and dihydroxyisoechinulin A (5), two benzene derivatives, siringin (6) and (3-methoxyphenyl) acetic acid (7), were isolated from the 70% acetone extract of the aerial parts of Euphorbia dracunculoides Lam. Their structures were elucidated on the basis of spectroscopic evidence and comparison with literature reports. The absolute configuration of 1 was deduced by comparing experimental and calculated ECD spectra. Among them, compounds 4 and 5 were first obtained from the plant source. In addition, the ¹³C NMR data of compound 2 was reported for the first time.
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