Palladium-catalyzed oxidative 6-exo-trig cyclization of 1,6-enynes: facile synthesis of bicyclo[4.1.0]heptan-5-ones
2015
Liu, Bang | Song, Ren-Jie | Ouyang, Xuan-Hui | Li, Yang | Hu, Ming | Li, Jin-Heng
We here describe a new palladium-catalyzed oxidative 6-exo-trig cyclization of 1,6-enynes at room temperature using tBuONO as an oxidant for the synthesis of 3-bicyclo[4.1.0]heptan-5-ones. This cascade strategy involves the hydration, cyclization and cyclopropanation sequence, and represents a new transition-metal-catalyzed oxidative cyclization of 1,6-enynes in a 6-exo-trig fashion.
显示更多 [+] 显示较少 [-]AGROVOC关键词
书目信息
出版者
The Royal Society of Chemistry
其它主题
Ambient temperature
语言
英语
类型
Journal Article; Text
2024-02-28
MODS