Folic acid-functionalized fluorescent gold nanoclusters with polymers as linkers for cancer cell imaging

Qiao, Juan; Mu, Xiaoyu; Qi, Li; Deng, Jingjing; Mao, Lanqun

Folic acid-functionalized fluorescent gold nanoclusters with polymers as linkers for cancer cell imaging

2013

Qiao, Juan | Mu, Xiaoyu | Qi, Li | Deng, Jingjing | Mao, Lanqun

A novel nano-conjugate containing ultrasmall water-soluble AuNCs protected by ovalbumin as the fluorescent part, folic acid as the targeting ligand and a homopolymer N-acryloxysuccinimide as the linker has been investigated. Moreover, specific staining of HeLa cells by the nano-conjugate has been demonstrated.

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