Asymmetric iridium-catalyzed hydrogenation of 2-methylindole using phosphite ligands
2014
Lyubimov, Sergey E. | Ozolin, Dmitry V. | Davankov, Vadim A.
The iridium-catalyzed asymmetric hydrogenation of 2-methylindole using monodentate phosphites and amidophosphites as ligands was examined. The use of iodine as the additive resulted in increased enantioselectivity and conversion in the iridium-catalyzed hydrogenation of 2-methylindole. Full conversion and up to 80% ee were obtained with a catalyst based on a phosphite ligand.
显示更多 [+] 显示较少 [-]AGROVOC关键词
书目信息
出版者
Elsevier Ltd
其它主题
Enantioselectivity; Phosphites; 2-methylindole; Asymmetric hydrogenation
语言
英语
类型
Journal Article; Text
2024-02-28
MODS