Evaluation of Corn Furan Fatty Acid Putative Endocrine Disruptors on Reproductive Performance in Adult Female Chickens
2006
Wilhelms, K.W. | Kraus, G.A. | Schroeder, J.D. | Kim, J.W. | Cutler, S.A. | Rasmussen, M.A. | Anderson, L.L. | Scanes, C.G.
Based on evidence from rodent models, it was hypothesized that furan fatty acids found in corn would inhibit reproduction in the laying hen. An isomeric mixture of furan fatty acids [9, (12)-oxy-10,13-dihydroxystearic acid and 10, (13)-oxy-9,12-dihydroxystearic acid] was administered for a period of 3 wk via the diet (1 and 3 ppm) at levels greater than those in corn to 20-wk-old pullets. There were no overt indications of acute or chronic toxicity (no effects on mortality, feed intake, or average daily gain). Similarly, there was no dose-dependent effect on reproductive parameters [egg production, egg weight, shell thickness, ovarian weight, number or weight of large yolky preovulatory follicles, and number of small yellow follicles (4-8 mm in diameter)]. The present data do not suggest that furan fatty acids are a cause of concern to the poultry industry.
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