Reprogramming extracellular vesicles with engineered proteins
2020
Shi, Xiaojing | Cheng, Qinqin | Zhang, Yong
Extracellular vesicles (EVs) have been emerging as a new class of cell-free therapy for the treatment of a variety of diseases, including cancer, tissue injuries, and inflammatory diseases. Reprograming native EVs by genetic engineering and other approaches offers an attractive prospect of extending therapeutic capabilities of EVs beyond their natural functions and properties. In this review article, we survey the state-of-the-art methods of EVs engineering and summarize major therapeutic applications of the reprogrammed EVs.
显示更多 [+] 显示较少 [-]AGROVOC关键词
书目信息
出版者
Elsevier Inc.
其它主题
Drug delivery; Therapeutics; Extracellular vesicles; Cell-free therapy; Fusion protein; Protein engineering
语言
英语
类型
Journal Article; Text
2024-02-28
MODS