A novel Campylobacter jejuni two-component regulatory system important for temperature-dependent growth and colonization
1999
Bras, A.M. | Chatterjee, S. | Wren, B.W. | Newell, D.G. | Ketley, J.M.
Campytobacter jejuni colonizes the intestines of domestic and wild animals and is a common cause of human diarrheal disease. We identified a two-component regulatory system, designated the RacR-RacS (reduced ability to colonize) system, that is involved in a temperature-dependent signalling pathway. A mutation of the response regulator gene racR reduced the organism's ability to colonize the chicken intestinal tract and resulted in temperature-dependent changes in its protein profile and growth characteristics.
显示更多 [+] 显示较少 [-]AGROVOC关键词
书目信息
Journal of bacteriology
卷
181
期
10
页码
3298
- 3302
ISSN
0021-9193
其它主题
Racs gene; Molecular sequence data; Regulon; Structural genes; Sensory histidine kinase; Experimental infections; Insertional; Trans-activators; Genbank/af053960; Bacterial; Signal transduction; Response regulators; Nucleotide sequences; Growth & development; Genbank/af053961; Protein kinases; Repressor proteins; Colonization; Regulation; Racr gene; Molecular; Microbial; Colony count; Two-dimensional; Molecular sequence data
语言
英语
类型
Journal Article; Text
2024-02-28
MODS