Comparison of β-carotene loaded marine and egg phospholipids nanoliposomes
2020
Hassane Hamadou, Alkassoumi | Huang, Wen-Can | Xue, Changhu | Mao, Xiangzhao
Encapsulation using nanoliposomes is widely recognized as an effective technique to protect sensitive bioactive compounds from adverse processing or gastrointestinal conditions. In this study, marine phospholipids (MPL) nanoliposomes containing β-carotene were prepared as novel carriers by thin-film evaporation method and their characteristics were compared with traditional egg phosphatidylcholine (EPC) nanoliposomes. Initially, the average size of nanoliposomes was in the range of 162.86–365.81 nm and MPL nanoliposomes showed lower sizes compared to EPC nanoliposomes. A good size distribution and homogeneous dispersion for MPL nanoliposomes was also observed. The highest encapsulation efficiency (EE) recorded for MPL nanoliposomes was 99.06% compared to 96.53% for EPC nanoliposomes. Both types of nanoliposomes were able to inhibit lipid peroxidation but the highest inhibition was recorded for MPL nanoliposomes (42.9%) and the lowest (10.26%) for their EPC counterparts. Overall, MPL nanoliposomes showed higher stability at 4 °C for 70 days. Therefore, MPL can be explored for production of nanoliposomal systems as carriers for delivery of sensitive bioactive compounds in the food industry.
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