The ecdysteroids from the tobacco hornworm during pupal-adult development five days after peak titer of molting hormone activity | Ecdysteroids from the tobacco hornworm [Manduca sexta] during pupal-adult development five days after peak titer of molting hormone activity
1979
Kaplanis, J.N. | Thompson, M.J. | Dutky, S.R. | Robbins, W.E.
Six naturally occurring C27 ecdysteroids were isolated and identified from the tobacco hornworm during pupal-adult development five days after peak titer of molting hormone activity. In order of decreasing quantities the hormones were: 20,26-dihydroxyecdysone, 3-epi-20-hydroxyecdysone, 20-hydroxyecdysone, 3-epi-20,26-dihydroxyecdysone, 3-epi-ecdysone, and ecdysone. 20-Hydroxyecdysone, in an earlier study, was the major molting hormone present at peak titer during pupal-adult development. The major ecdysteroid present during embryonic development in this insect, 26-hydroxyecdysone, was not detected. The copresence of all six of these ecdysteroids from a single developmental stage of an insect provides information on the metabolic interrelationships that exist among these steroids and on their possible function(s) in insects. The 3α-ecdysteroids were far less active than the 3β-epimers in the house fly assay. The significance of epimerization is discussed.
显示更多 [+] 显示较少 [-]