Anti-cytokine therapies for psoriasis
2011
Nograles, Kristine E. | Krueger, James G.
Current approaches for the treatment of psoriasis with anti-cytokine therapies involve the blockade of TNF-α, or the p40 sub-unit of IL-12 and IL-23. However, the field is currently evolving to test more selective antagonists, such as anti-IL-23p19, IL-17 and other inflammatory cytokines. Here we discuss our current understanding of dendritic cell and T cell subsets that are relevant in psoriasis, and the pharmacologic strategies that temper their activity in this disease.
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书目信息
出版者
Elsevier Inc.
其它主题
Tumor necrosis factor-alpha; Interleukin-12; Interleukin-23; Antagonists; Psoriasis; Interleukin-17
语言
英语
类型
Journal Article; Text
2024-02-29
MODS