Regioselective synthesis of substituted piperidine-2,4-diones and their derivatives via Dieckmann cyclisations
2015
Marson, Charles M. | Yau, Kin Cheung
A flexible route to piperidine-2,4-diones variously substituted at the 6-, 5,6- and 2,6-positions, both with and without 1-substitution, is described; no N-protective group is required. A related regioselective Dieckmann cyclisation is also described that uses Davies' α-methylbenzylamine auxiliary and affords 6-substituted piperidine-2,4-diones enantioselectively.
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书目信息
出版者
Elsevier Ltd
其它主题
Piperidine-2; 4-diones; Regioselective synthesis; Enantioselective synthesis; Dieckmann cyclisation
语言
英语
类型
Journal Article; Text
2024-02-29
MODS