Pd(II)-Catalyzed Synthesis of Furo[2,3-b]pyridines from β-Ketodinitriles and Alkynes via Cyclization and N–H/C Annulation
2022
Rakshit, Amitava | Dhara, Hirendra Nath | Sahoo, Ashish Kumar | Alam, Tipu | Patel, Bhisma K.
A Pd(II)-catalyzed synthesis of furopyridines has been developed from β-ketodinitriles and alkynes via an unusual N–H/C annulation. The participation of both the nitrile groups and the concurrent construction of furan and pyridine rings through the formation of C–C, C═C, C–O, C–N, and C═N bonds are the important features. The synthetic applicability is further demonstrated through a series of postsynthetic alterations.
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书目信息
Organic letters
卷
24
期
20
页码
3741
- 3746
ISSN
1523-7052
出版者
American Chemical Society
其它主题
Alkynes
语言
英语
类型
Journal Article; Text
2024-02-29
MODS