Synthesis of Sulfonamide-Based Ynamides and Ynamines in Water
2020
Zhao, Lei | Yang, Hongyi | Li, Ruikun | Tao, Ye | Guo, Xiao-Feng | Anderson, Edward A. | Whiting, Andrew | Wu, Na
Ynamides, though relatively more stable than ynamines, are still moisture-sensitive and prone to hydration especially under acidic and heating conditions. Here we report an environmentally benign, robust protocol to synthesize sulfonamide-based ynamides and arylynamines via Sonogashira coupling reactions in water, using a readily available quaternary ammonium salt as the surfactant.
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书目信息
Journal of organic chemistry
卷
86
期
2
页码
1938
- 1947
ISSN
1520-6904
出版者
American Chemical Society
其它主题
Ammonium salts; Organic chemistry
语言
英语
类型
Journal Article; Text
2024-02-29
MODS