Analysis of the presence of anti-inflammatories drugs in surface water: A case study in Beberibe river - PE, Brazil
2019
Veras, Tatiane Barbosa | Luiz Ribeiro de Paiva, Anderson | Duarte, Marta Maria Menezes Bezerra | Napoleão, Daniela Carla | Cabral, Jaime J. P. (Jaime Joaquim Pereira)
The contamination of water by drug residues has occurred all over the world, arousing interest of the scientific community due to possible deleterious effects that can cause to human health and to environment. Conventional treatment of water does not remove drug residues as they are not legislated. Knowledge about the concentrations of exposure of drug residues in aquatic matrices generates subsidies for these compounds to become candidates for future regulation. Beberibe river watershed, due to urbanization, has been affected by domestic effluents causing problems in the quality of water bodies. An old point of abstraction for public supply was abandoned some years ago and the uptake was installed upstream at a new point without presence of domestic effluents. In this context, the present study analyzed the presence of anti-inflammatories drugs in two points of Beberibe river, being Point 1 in a preserved area, not presenting urbanization in its surroundings, and Point 2 in an area that suffers with intense urbanization. During 6 months of surface water collection, contamination by diclofenac and paracetamol were evaluated. The analyzes were performed with using Shimadzu HPLC equipment, with an ULTRA C18 column with reverse phase analysis (5 μm; 4.6 × 250 mm) and UV detection (SPD - 20 A) for wavelengths of 285 nm. Diclofenac had higher concentrations than paracetamol, being 0.193 and 0.042 mg L-1, respectively. The highest levels of concentration were presented in Point 2, probably due to anthropogenic interference. In addition, it was observed that the highest concentrations were detected during drought periods.
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