An inositol phosphate as a calcium absorption enhancer in rats
1998
Shen, X. | Weaver, C.M. | Kempa-Steczko, A. | Martin, B.R. | Phillippy, B.Q. | Heaney, R.P.
Certain inositol phosphate breakdown compounds have been shown to chelate and increase the solubility of minerals. A rat model using femur uptake of 45Ca was tested for its ability to screen the effect of inositol phosphytate breakdown products on enhancing calcium absorption. Phytate was shown to inhibit calcium absorption in a dose-related manner. A significant enhancing effect of 1,2,3,6-tetraphosphate on calcium absorption was found at the highest level studied (P < 0.05), which suggests that this compound may be a candidate for enhancing calcium absorption.
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