New antioxidant bibenzyl derivative and isoflavonoid from the Tunisian Salsola tetrandra Folsk
2012
Beyaoui, Ahlem | Chaari, Atef | Ghouila, Hatem | Ali Hamza, M’hamed | Ben Jannet, Hichem
Two new phytochemical compounds, Tetranins A and B, 1-(3,5′-dihydroxy-4′-méthoxyphenyl)-2-phenylethanol 1 and 5,2′-dihydroxy-5′-methoxy-6,7-methylenedioxy-isoflavone 2, were isolated from the EtOAc extract of Salsola tetrandra roots. They exhibited a significant antioxidant effect in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and 2,2′-azinobis (3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assays. Their structures were elucidated by extensive spectroscopic methods including 1-D-(¹H and ¹³C) and 2-D-NMR experiments (CHcorr, HMBC, ¹H-¹H COSY and NOESY) as well as high-resolution ES-MS and they were found to be quite active as antioxidants in the DPPH and ABTS assays.
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