Use of nonimaging nuclear medicine techniques techniques to assess the effect of flunixin meglumine on effective renal plasma flow and effective renal blood flow in healthy horses

Held, J.P.; Daniel, G.B.

Use of nonimaging nuclear medicine techniques techniques to assess the effect of flunixin meglumine on effective renal plasma flow and effective renal blood flow in healthy horses

1991

Held, J.P. | Daniel, G.B.

The effect of flunixin meglumine on renal function was studied in 6 healthy horses by use of nonimaging nuclear medicine techniques. Effective renal plasma flow (ERPF) and effective renal blood flow (ERBF) were determined by plasma clearance of 131I-orthoiodohippuric acid before and after administration of flunixin meglumine. Mean ERPF and ERBF was 6.03 ml/min/kg and 10.7 ml/min/kg, respectively, before treatment and was 5.7 ml/min/kg and 9.7 ml/min/kg, respectively, after treatment. Although ERPF and ERBF decreased after flunixin meglumine administration, the difference was not statistically significant.

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