Hormesis commonly observed in the assessment of aneuploidy in yeast

Calabrese, Edward J.

Hormesis commonly observed in the assessment of aneuploidy in yeast

2017

Calabrese, Edward J.

Extensive dose response studies have assessed the potential of toxic chemical agents to induce aneuploidy in the yeast model. An assessment of such findings revealed that hormetic-like biphasic dose responses were commonly observed. A preliminary estimate of the frequency of the hormetic responses using a priori entry and evaluative criteria was approximately 65–80%. These findings suggest the possibility of hormetic effects being extended to genotoxic endpoints.

显示更多 [+]