Helicase: mystery of progression
2007
Gaur, Rajneesh Kumar
Helicases mode of unwinding the nucleic acids and translocation along single stranded nucleic acids is still a subject of great curiosity. Based on the energy transduction and electrophilic interactions, we present a model to explain the mode of action of active helicases. This model considers that both strand separation as well as translocation is active processes fueled by NTP hydrolysis. The model proposes that the translocation appears to involve creeping of helicase over the ssNA lattice rather than inchworm movement.
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书目信息
Molecular biology reports
卷
34
期
3
页码
161
- 164
ISSN
0301-4851
出版者
Elsevier B.V.
其它主题
Protein conformation; Unwinding nucleic acid; Hypothesis; Dna helicases; Nucleic acid denaturation; Chemical model; Protein binding; Helicase; Nucleic acid conformation; Genetic
语言
英语
注释
Includes references
类型
Journal Article; Text
2024-02-29
MODS