Regio-specific synthesis of new 1-(tert-butyl)-1H-pyrazolecarboxamide derivatives
2017
Ruatta, Santiago Matías | Murguía, Marcelo César | Ramírez de Arellano, Carmen | Fustero, Santos
Regio-specific and non-regiospecific condensation reactions on 1,3-dicarbonyl compounds rendered 1,3,5-trisubstituted pyrazoles. Herein, the control of regio-specificity was a significant improvement in pyrazole research. A high yield acylation of poorly nucleophilic aryl amines, which resulted in mono- or diacylated products depending on the reaction conditions, is described. As a result, a library of potentially bioactive compounds was obtained.
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书目信息
出版者
American Phytopathological Society
其它主题
Diacylation; Regio-specific condensation; Arylamine acylation; Pyrazole carboxamide; Tert-butyl hydrazine; Pyrazoles; Condensation reactions
语言
英语
注释
Pre-press version
类型
Journal Article; Text
2024-02-29
MODS