Carbohydrate-induced thermogenesis in man
1986
Jequier, E.
A brief review examines the methodology and findings of recent studies on glucose-induced thermogenesis (GIT) in humans. Use of the glucose clamp during simultaneous infusion of glucose and insulin aids permits studies of glucose metabolism during steady-state blood glucose-insulin levels. Another method, open-circuit indirect calorimetry, can be used to monitor energy expenditure. Coupling of these 2 methods can be used to determine the rate of glucose storage. A study of GIT in young adults found that GIT accounted for 12-15% of the energy content of the glucose load. The reviewed studies support 2 components of GIT, viz.: an "obligatory" and a "facultative" component, associated with the energy cost of glucose storage and energy dissipation, respectively.(wz)
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