Nutritional anemias: Relationship to genetic and pharmacological factors
1981
Dallman, Peter R.
Some common genetic and pharmacological factors that influence the evaluation of anemia are reviewed. On the basis of this review, it was concluded that ethnic background and history of use of common drugs should be included in an individuals's nutritional history documentation when a nutritional anemia diagnosis is considered. Evidence concerning genetic (or racial) and pharmacologic factors is discussed. Two genetic or racial factors must be considered in anemia screening: thalassemia (affecting synthesis rate of hemoglobin globin chains); and potentially low normal hemoglobin levels in blacks. In addition, 2 common pharmacologic factors also should be considered: the use of contraceptives and the use of aspirin. Use of the former by women can be a major influence on iron or folate nutrition; while aspirin, taken in large doses causes intestinal bleeding. All 4 of these factors are discussed in detail. (wz)
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