Adipocyte differentiation is regulated by a prostaglandin liganded to the nuclear peroxisome proliferator-activated receptor
1996
Wolf, G.
Adipocyte differentiation and the homeostasis of fat cell number are regulated by a nuclear receptor protein, the peroxisome proliferator-activated receptor (PPARgamma) The endogenous ligand is thought to be 15-deoxy-delta(12,14)-prostaglandin J2. Thiazolidinedione, an antidiabetic drug, closely mimics the action of the prostaglandin, suggesting a regulatory role by the prostaglandin and PPARgamma both in adipocyte differentiation and in glucose homeostasis.
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书目信息
Nutrition reviews
卷
54
期
9
页码
290-292
- 292
ISSN
0029-6643
出版者
Edizioni ETS
其它主题
Drug effects; Hypoglycemic agents; Cell line; Adipocytes; Organic sulfur compounds; Adipocytes; Nuclear proteins; Regulation; Hypoglycemic agents; Cytoplasmic and nuclear; Triazolidinediones; Thiazolidinediones
语言
英语
类型
Journal Article; Text
2024-02-29
MODS