Synthesis and applications of 4-substituted 1-(4-iodophenyl)pyrrolidine-2,5-diones
2015
Ali, Bakhat | Shamim, Anwar | Vasconcelos, Stanley N.S. | Stefani, Hélio A.
The synthesis of 4-substituted 1-(4-iodophenyl)pyrrolidine-2,5-dione derivatives was achieved through an addition reaction between amines and a thiol in the presence of PMDTA as a base and a copper salt. The derivatives containing a terminal acetylene moiety were converted to the corresponding 1,4-triazolyl derivatives. The 1-(4-iodophenyl)pyrrolidine-2,5-dione derivatives were functionalized through oxidation alkylation and allylation reactions. In general, the compounds were obtained in moderate-to-good yields.
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书目信息
Tetrahedron letters
ISSN
0040-4039
出版者
Elsevier Ltd
其它主题
Functionalization; Moieties; Maleimide; Aminopyrrolidine; Alkylation; Allylation; 4-triazole; Chemical derivatives
语言
英语
类型
Journal Article; Text
2024-02-29
MODS