SnapShot: Talin and the Modular Nature of the Integrin Adhesome
2014
Ye, Feng | Lagarrigue, Frederic | Ginsberg, Mark H.
Integrin αβ transmembrane heterodimers play central roles in metazoan development and physiology by mediating adhesion and by transmitting forces and biochemical signals across the plasma membrane. In this SnapShot, we present a simplified “modular” view of the integrin adhesome, centered on the talin-integrin interaction, and provide examples of how this view can help to unravel the adhesome’s remarkable functional diversity and plasticity.
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书目信息
Cell
ISSN
0092-8674
出版者
Springer-Verlag
其它主题
Talin; Integrins; Functional diversity; Plasma membrane
语言
英语
许可
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类型
Journal Article; Text
2024-02-29
MODS